Chief Computational Chemist
Há 6 dias
Job Summary:
- We are seeking a highly motivated, talented and creative scientist with experience in computational chemistry to lead the development of stage-appropriate models using advanced computational techniques.
- The ideal candidate will collaborate with discovery colleagues to design and optimize oral and developable macrocyclic peptides.
About the Role:
Molecular Profiling and Drug DeliveryThis function is accountable for deliverables across various stages of drug discovery and development.
Our team utilizes state-of-the-art automation and computational tools supported by expertise in biopharmaceutics, drug delivery and solid-state chemistry to collaboratively design and progress candidates with higher probability of success into development.
From candidate selection through clinical proof of concept and product launch, our scientists work in cross-functional teams to identify the commercial solid form of the active pharmaceutical ingredient (API) and establish structure-property-performance correlations to help deliver robust commercial processes and align control strategies.
As a member of our team, you will be working collaboratively with other functions within Development Sciences and Discovery Sciences to advance first-in-class and best-in-class clinical candidates.
Key Responsibilities:- In collaboration with Discovery Research and Development Sciences project teams, utilize advanced computational tools towards the design, optimization and profiling of macrocyclic peptides, large and small molecule drug candidates.
- Advance computational chemistry capabilities through innovation and implementation of new methodologies and workflows towards capturing key developability properties such as permeability, stability and solubility.
- Bachelors, Masters or PhD with 8+ (BS), 5+ (MS) and 0-3 (PhD) years of experience in computational chemistry, computer science, biophysics, chemical engineering or related field.
- Knowledge in one or more areas of the computational chemistry discipline such as quantum mechanics, molecular dynamics, structure-based design, ligand-based design and physicochemical property prediction.
About Us:
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.
We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience and eye care – and products and services in our portfolio.
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