Reimbursement & Health Economics Sr. Manager (Latam)

General Summary

The LATAM Reimbursement & Health Economics, Sr. Manager will be the first dedicated role of

its kind in the region, responsible for the development and execution of reimbursement strategies

and health economics initiatives across Latin America. Based in São Paulo, Brazil, this role will

operate with a high degree of autonomy and serve as the primary point of contact for

reimbursement and HEOR in LATAM, while working closely with local, regional, and cross-

functional teams. The focus will be on building strong payer and stakeholder relationships,

developing compelling economic value propositions, and enabling reimbursement to Penumbra's

innovative portfolio.

Specific Duties and Responsibilities:

Reimbursement:

• Develop and implement reimbursement strategies that will maintain existing products

and support the successful launch long-term adoption of Penumbra products in LATAM.*

• Write and submit reimbursement dossiers and/or health technology assessments (HTA)

for Penumbra products. Communicate letters when needed to health authorities. *

• Serve as the regional expert in government reimbursement policies and areas of third-

party reimbursement, and payer processes. *

• Provide reimbursement guidance to internal stakeholders (marketing, sales, clinical,

regulatory) and external customers (physicians, payers, trade associations).

• Partners with Commercial, Marketing, Regulatory, R&D, Clinical, and Legal to develop

strategies that establish a compelling economic value proposition for Penumbra products

and support and protect price points. *

• Develop reimbursement tools, communication materials and payer engagement

strategies.

• Travel as needed to key markets to engage with relevant stakeholders (e.g. health

authorities, payers, etc.) and represent Penumbra at congresses.

Health Economics:

• Identify HEOR evidence gaps and develop strategies to generate local and regional

evidence to support Penumbra's technologies. *

• Monitor evolving trends in health economics, HTA, and reimbursement policies in

LATAM providing insights and recommendations to senior management.

• Adapt and deliver economics models using local data and work with sales/marketing to

use the health economics value proposition to support uptake of the therapies.

• Develop and deliver real-world evidence (RWE) analysis, burden-of-illness analyses,

and literature/systematic reviews.

• Prepare clinical and economic dossiers to support submissions to health authorities and

payer organizations. *

• Develop and deliver HEOR-related training to sales, marketing, clinical, regulatory, and

legal to increase awareness and understanding of HEOR competency and its role in

supporting market adoption of Penumbra's technologies.

General:

• Adhere to the Company's Quality Management System (QMS) as well as domestic and

global quality system regulations, standards, and procedures. *

• Understand relevant security, privacy and compliance principles and adhere to the

regulations, standards, and procedures that are applicable to the Company. *

• Ensure other members of the department follow the QMS, regulations, standards, and

procedures. *

• Perform other work-related duties as assigned.

*Indicates an essential function of the role

Position Qualifications

Minimum education and experience:

• Bachelor's degree in economics, pharmacy, public health, health services research or

related with 7+ years of experience in reimbursement and HEOR, or equivalent

combination of education and experience.

Additional qualifications:

• Advanced degree (Master's or PhD) in Health Economics, Public Health, Epidemiology,

or Biostatistics strongly preferred.

• Languages: Fluent in Portuguese, Spanish, and English.

• Proven track record of developing and submitting reimbursement dossiers in LATAM,

with strong experience in Brazil.

• Experience in medical devices is strongly preferred; hybrid backgrounds from

pharma/biotech with robust HTA experience will also be considered. Direct experience

working with vascular therapies devices is highly desirable

• Demonstrated success in developing and adapting economic models (cost-

effectiveness, budget impact).

• Demonstrated success developing HEOR evidence strategies aligned with business

needs, including the ability to influence senior leadership.

• Hands-on experience with RWE generation and evidence synthesis.

• Strong analytical and strategic mindset with ability to translate evidence into business

impact.

• Understanding of medical/clinical research methods and publication interpretation and

ability to use evidence to support value proposition.

• Excellent communication skills to influence senior leaders, payers, and cross-functional

stakeholders

• High emotional intelligence, organizational skills, and ability to manage multiple priorities

simultaneously.

About Penumbra, Inc.

Penumbra, Inc. is a global healthcare company focused on developing, manufacturing, and marketing innovative medical devices and technologies that address challenging unmet needs in healthcare. Founded in 2004 and headquartered in Alameda, California, Penumbra operates in more than 100 countries, with a mission to help patients and healthcare providers by designing products that restore blood flow and improve the quality of life for people affected by vascular and neurovascular conditions.

The company is a recognized leader in interventional therapies, including neurovascular thrombectomy, peripheral thrombectomy, and embolization technologies. Its product portfolio includes the Penumbra System, Indigo System, RED Reperfusion Catheters, and REAL Immersive System—a groundbreaking virtual reality platform designed to support neurorehabilitation and mental health.

Driven by innovation, Penumbra combines advanced engineering, rigorous clinical research, and close collaboration with healthcare professionals worldwide. Its purpose is simple yet profound: to inspire and advance healthcare through innovation and compassion.