Clinical Laboratory Scientist

1 semana atrás


Laguna, Brasil PreludeDx Tempo inteiro

We are seeking a highly motivated and skilled licensed CLS to join our team. The ideal candidate will have experience in running Next Generation Sequencing (NGS) and knowledge of molecular biology techniques.

Essential Responsibilities:

  • Ensure that the equipment is calibrated, maintained, and operated according to the manufacturer's guidelines and standard operating procedures.
  • Adheres to the CAP, CLIA and NYS regulations.
  • Run protocols for sample collection, processing, storage, and tracking in LIMs to ensure the integrity and traceability of the samples throughout the NGS workflow.
  • Run clinical and R&D samples for NGS and molecular biology techniques, including microdissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality control measures with appropriate NGS controls.
  • Perform and train other CLS's on established NGS and molecular biology procedures, including macrodissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, and data analysis, including quality control measures.
  • Perform validation testing to ensure with selected reagents and controls to ensure the assay meets the required performance specifications.
  • Perform validation studies to assess the performance characteristics of the NGS assay, including sensitivity, specificity, accuracy, precision, and reproducibility.
  • Analyze and interpret data using appropriate statistical methods and software, including sensitivity, specificity, accuracy, precision and reproducibility.
  • Maintain accurate records and documentation of experiments and results.
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.

Requirements

  • Minimum 4 years as a certified or licensed clinical laboratory scientist
  • California Clinical Laboratory Scientist (Highly Preferred: California Clinical Genetic Molecular Biologist Scientist license - CGMBS.)
  • Must be well-organized, open-minded, decisive, and flexible. They must be able to communicate well with others, and work as a team. Good writing skills and and extensive computer experience are necessary
  • Experience with Macrodissection, RNA extraction and downstream analysis
  • Strong experience in development of targeted library, conducting sequencing NGS library preparation, sequencing, and data analysis
  • Experience in project management and organization
  • Excellent record-keeping and documentation skills
  • Strong communication skills and ability to work in a team-oriented environment
  • Validation and SOP writing experience a plus
  • Must have superior work ethic, driven and be results oriented
  • Comfortable in a fast-paced environment
  • Excellent oral and written communication skills
  • Preferred Bachelor's or Master's degree in Molecular Biology, Biochemistry, or related field
  • Anatomic or Clinical Pathology experience
  • Prior experience with NextGen sequencing instruments.
  • Minimum of 4 years of molecular and histology experience within an anatomic pathology laboratory or clinical laboratory.
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