
Clinical Laboratory Scientist
1 semana atrás
We are seeking a highly motivated and skilled licensed CLS to join our team. The ideal candidate will have experience in running Next Generation Sequencing (NGS) and knowledge of molecular biology techniques.
Essential Responsibilities:
- Ensure that the equipment is calibrated, maintained, and operated according to the manufacturer's guidelines and standard operating procedures.
- Adheres to the CAP, CLIA and NYS regulations.
- Run protocols for sample collection, processing, storage, and tracking in LIMs to ensure the integrity and traceability of the samples throughout the NGS workflow.
- Run clinical and R&D samples for NGS and molecular biology techniques, including microdissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality control measures with appropriate NGS controls.
- Perform and train other CLS's on established NGS and molecular biology procedures, including macrodissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, and data analysis, including quality control measures.
- Perform validation testing to ensure with selected reagents and controls to ensure the assay meets the required performance specifications.
- Perform validation studies to assess the performance characteristics of the NGS assay, including sensitivity, specificity, accuracy, precision, and reproducibility.
- Analyze and interpret data using appropriate statistical methods and software, including sensitivity, specificity, accuracy, precision and reproducibility.
- Maintain accurate records and documentation of experiments and results.
Requirements
- Minimum 4 years as a certified or licensed clinical laboratory scientist
- California Clinical Laboratory Scientist (Highly Preferred: California Clinical Genetic Molecular Biologist Scientist license - CGMBS.)
- Must be well-organized, open-minded, decisive, and flexible. They must be able to communicate well with others, and work as a team. Good writing skills and and extensive computer experience are necessary
- Experience with Macrodissection, RNA extraction and downstream analysis
- Strong experience in development of targeted library, conducting sequencing NGS library preparation, sequencing, and data analysis
- Experience in project management and organization
- Excellent record-keeping and documentation skills
- Strong communication skills and ability to work in a team-oriented environment
- Validation and SOP writing experience a plus
- Must have superior work ethic, driven and be results oriented
- Comfortable in a fast-paced environment
- Excellent oral and written communication skills
- Preferred Bachelor's or Master's degree in Molecular Biology, Biochemistry, or related field
- Anatomic or Clinical Pathology experience
- Prior experience with NextGen sequencing instruments.
- Minimum of 4 years of molecular and histology experience within an anatomic pathology laboratory or clinical laboratory.
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